Improvement of Restless Legs Syndrome by Varenicline as Antismoking Treatment
1IRCCS Neuromed Istituto Neurologico Mediterraneo Sleep Medicine Center Pozzilli (Is), Italy; 2Università di Roma Tor Vergata – Neurophysiopathology Department Sleep & Epilepsy Centre, Rome, Italy
Varenicline is a partial agonist at the α4β2 nicotinic acetylcholine receptor effective as smoking cessation pharmacotherapy. We present a familial case of severe restless legs syndrome (RLS) resistant to polytherapy who showed a consistent and effective amelioration of RLS symptoms after introduction of varenicline as antismoking drug.
Romigi A; Vitrani G. Improvement of restless legs syndrome by varenicline as antismoking treatment. J Clin Sleep Med 2013;9(10):1089-1090.
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