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Volume 10 No. 07
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Accepted Papers

Case Reports

Resolution of Severe Obstructive Sleep Apnea after Treatment of Anti-Muscle Kinase Receptor-Positive Myasthenia Gravis Despite 60-Pound Weight Gain

Michael Morgenstern, M.D.; Effie Singas, M.D.; Bashar Zleik, M.D.; Harly Greenberg, M.D., F.A.A.S.M.
Division of Pulmonary, Critical Care and Sleep Medicine, Hofstra North Shore-LIJ School of Medicine, New Hyde Park, NY

Obstructive sleep apnea (OSA) in patients with myasthenia gravis (MG) may be caused by reduced pharyngeal dilator muscle activity. We report a patient with anti-muscle kinase receptor MG with severe OSA and hypoventilation that resolved upon successful treatment of MG despite a 60-lb weight gain.


Morgenstern M, Singas E, Zleik B, Greenberg H. Resolution of severe obstructive sleep apnea after treatment of anti-muscle kinase receptor-positive myasthenia gravis despite 60-pound weight gain. J Clin Sleep Med 2014;10(7):813-814.

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