Current Knowledge/Study Rationale: This work was designed to explore the possible relationship between obstructive sleep apnea (OSA) and alterations of the left ventricular mass (LVM) in patients with morbid obesity. The influence of gender, menopausal status, body composition, and cardiovascular risk factors were also taken into consideration. The results show a high prevalence of sleep apnea and LVM alterations in this population, especially for men and PostM women. Interestingly, the apnea-hypopnea index related to LVM independently of age, gender, menopausal status, and other cardiovascular risk factors, including hypertension. These results support a direct effect of OSA on LVM, and suggest that LVM should be assessed in all patients with morbid obesity and OSA, particularly men and postmenopausal women.
Study Impact: Morbid obesity is frequently associated to left ventricular mass alterations and obstructive sleep apnea. In this study we aimed to assess a possible direct relation between both cardiovascular risk factors and the influence played by complications such as hypertension and type 2 diabetes, often associated with obesity.