Case Reports
Sodium Oxybate and Sleep Apnea: A Clinical Case
http://dx.doi.org/10.5664/jcsm.1480
Sarah Hartley, B.M., B.Ch.; Maria-Antonia Quera-Salva, M.D.; Mourad Machou, M.D.
AP-HP Hôpital Raymond Poincaré, Sleep Unit, Physiology Department, Versailles-St Quentin en Yvelines University, France
Sodium oxybate (GHB, Xyrem, Jazz Pharmaceuticals) is used to treat cataplexy in patients with narcolepsy. We report the case of a middle aged, normo-ponderal narcoleptic woman without risk factors who developed reversible sleep apnea and objective sleepiness when treated by sodium oxybate, with an apnea-hypopnea index (AHI) of 19.7 on sodium oxybate and AHI 4.8 without treatment. Despite a subjective improvement in vigilance, mean sleep latency on MWT decreased from 21 minutes to 8 minutes on sodium oxybate.
Citation:
Hartley S; Quera-Salva MA; Machou M. Sodium oxybate and sleep apnea: a clinical case. J Clin Sleep Med 2011;7(6):667-668.
Please login to continue reading the full article
Subscribers to JCSM get full access to current and past issues of the JCSM.
Login to JCSM
Not a subscriber?
Join the American Academy of Sleep Medicine and receive a subscription to JCSM with your membership